Development of a Species-Specific Coproantigen ELISA for Human Taenia solium Taeniasis

Development of a species-specific coproantigen ELISA for human Taenia solium taeniasis.

Taenia solium causes human neurocysticercosis and is endemic in underdeveloped countries where backyard pig keeping is common. Microscopic fecal diagnostic methods for human T. solium taeniasis are not very sensitive, and Taenia saginata and Taenia solium eggs are indistinguishable under the light microscope. Coproantigen (CoAg) ELISA methods are very sensitive, but currently only genus (Taenia...

Nested PCR for specific diagnosis of Taenia solium taeniasis.

Taeniasis due to Taenia solium is a disease with important public health consequences, since the larval stage is not exclusive to the animal intermediate, the pig, but also infects humans, causing neurocysticercosis. Early diagnosis and treatment of T. solium tapeworm carriers is important to prevent human cysticercosis. Current diagnosis based on microscopic observation of eggs lacks both sens...

Nested PCR for the Specific Diagnosis of Taenia solium Taeniasis

The parasitological, immunological and molecular diagnosis of human taeniasis with special emphasis on Taenia solium taeniasis

Human neurocysticercosis, caused by the larval stage of the tapeworm Taenia solium, is an important neurological disorder reported as a major cause of epilepsy. An important risk factor for neurocysticercosis is the presence of human T. solium carriers who, upon open defecation, disseminate tapeworm eggs, which are infective to both humans and pigs. In the latter, infection also results in cyst...

Sero-prevalence of Taenia solium cysticercosis and Taenia solium taeniasis in California, USA.

OBJECTIVES Taenia solium Cysticercosis is a leading cause of epilepsy and neurological disability in the developing world. It is caused by ingestion of the eggs of the tapeworm, T. solium Taeniasis. The prevalence of either T. solium Cysticercosis or T. solium Taeniasis in the United States in populations at risk is poorly understood. The primary objectives of this study are to perform the firs...